【摘要】 目的:了解食管癌术后胸腔胃排空功能和分泌功能的改变,探讨改善患者术后营养不良的措施。方法:用同位素技术对35例食管癌患者进行术前、术后胸腔胃排空功能的检测,同时,测定胃酸、血清胃泌素水平的变化及胃粘膜的病理改变,研究手术前后胃的生理改变。结果:术后胸腔胃泌酸功能明显减低(P<0.01),空腹血清胃泌素浓度明显升高(P<0.01),胸腔胃对半流质食物排空加快(P<0.05),萎缩性胃炎发生率明显增高。结论:食管癌切除全胃重建食管术,可不必常规行幽门成行术。适量服用稀盐酸、胃蛋白酶等可减轻患者术后消化不良症状、改善生活质量。更多还原

【Abstract】 Objective: To search the empting and secreting function of intrathoracic stomach after esophagectomy and find ways to improve patients’ digestive function. Methods: In 35 patients,empting function of intrathoracic stomach was studied with rediosiotopic technique preoperatively and postoperatively. Meanwhile, acid secretion, fasting serum gastrin (FSG), and pathologic changes of gastric mucosa were examined. Results: The empting of semisolid food from the intrathoracic stomach was faster significantly (P<0.05), the acid sereting function decreased, but the FSG increased (P<0.01) after esophagectomy. High incidence of atrophic gastritis was found in intrathoracic stomach. Conclusion: Pyloraplasty should not be performed routinely in construction of esophagus with stomach after esophagectomy, and a certain amount of diluted hydrochloric acid and pepsin should be given to reduce the indigestive symptoms and normalize patients’ digestive function.更多还原