【摘要】 目的　通过分析冠心病与非冠心病患者血清总胆红素、血脂及尿酸水平 ,探讨其在预测评估冠心病方面的临床意义。方法　 14 4例疑似冠心病患者 (CHD) ,经冠状动脉造影结果分为冠心病组 (CHD组 ) 92例和非冠心病组 (non CHD组 ) 5 2例 ,分别测定其血清总胆红素 (TBIL)、血脂各组分总胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白胆固醇 (HDL c)、低密度脂蛋白胆固醇 (LDL c)、载脂蛋白Al(ApoAl)、载脂蛋白B10 0 (ApoB)及尿酸 (UA)水平。结果　①血清TBIL水平 :CHD组低于non CHD组 (P <0 0 5 ) ;②血清脂质各组分 :TC、LDL c及ApoB水平CHD组高于non CHD组 (P <0 0 5 ) ,LDL c/HDL c及ApoB/ApoAl比值CHD组显著高于non CHD组 (P <0 0 1) ,其余指标在组间分布差异不显著 (P >0 0 5 ) ;③血清尿酸水平 :CHD组高于non CHD组 (P <0 0 5 )。结论　检测冠心病患者血清TBIL、UA和血清脂质各组分水平对预测评估冠心病有一定临床价值更多还原

【Abstract】 Objective To assess the clinic significance of serum bilirubin,lipids and uric acid in patients with coronary heart disease(CHD).Methods One-hundred and forty-four patients with suspected CHD were divided into CHD group(n=92)and non-CHD group(n=52) according to the result of coronary angiographic examination.Their serum concentration of total bilirubin,lipids items,including totol cholesterol (TC),triglycerides(TG),high density lipoprotein(HDL-c),low density lipoprotein (LDL-c),Apoprotein Al(Apo-Al) and Apoprotein B100(Apo-B) were measured and compared.Results ①The serum concentration of total bilirubin in CHD group was lower than that of non-CHD group(P<0.05).②The serum concentration of TC、 LDL-c and ApoB of CHD group were higher than those of non-CHD group(P<0.05);The ratio of LDL-c/HDL-c and Apo-B/Apo-Al were significant higher than those of non-CHD group(P<0.01)There were no statistical difference between two groups on other items(P>0.05).③The serum concentration of uric acid in CHD group was higher than that of non-CHD group(P<0.05).Conclusion Serum bilirubin,lipids and uric acid in patients with coronary heart disease(CHD) are important in evaluating the CHD.更多还原