【摘要】 目的评价病毒性肝炎患者的红细胞分布宽度(RDW)、平均红细胞体积(MCV)、平均血小板体积(MPV)、血小板分布宽度(PDW)等四项血常规参数的临床意义。方法采用全自动血细胞计数仪检测188例病毒性肝炎患者和16名健康人(对照组)的血常规参数,并同期采用全自动生化分析仪检测被测者的血清总胆红素(TBi)和白蛋白(Alb)以及采用全自动血凝仪检测血浆凝血酶原时间(PT)。结果慢性肝炎(CH)组、肝炎后肝硬化(LC)组和重症肝炎(HG)组的RDW均显著高于对照组,CH组、LC组的MCV显著高于对照组,MPV和PDW在各病毒性肝炎组与对照组之间无显著性差异;病毒性肝炎患者的RDW与其TBi、PT成显著直线正相关而与Alb成显著直线负相关,MCV与其PT成显著直线正相关而与其Alb成显著直线负相关。结论RDW、MCV对初步反映病毒性肝炎患者的肝功能损伤状况具有一定的临床价值。更多还原

【Abstract】 Objective To reevaluate the clinical significance of four blood routine parameters, RDW, MCV, MPV and PDW in patients with viral hepatitis. Methods The blood routine parameters of 188 cases with viral hepatitis and 16 healthy persons(as control group) were measured with automatic blood cell counter. The serum total bilirubin (TBi) and serum albumin (Alb) were detected with automatic biochemical analyzer and the plasma thrombin time (PT) was detected with automatic coagulometer. Results The parameter, RDW in chronic hepatitis (CH) group, hepatitis liver cirrhosis (LC) group and hepatitis gravis were markedly higher than that in the control group. The parameter, MCV in CH group and LC group were notably higher than that in the control group. However, the parameter MPV and PDW showed no significant different between the patients and the control group. In patients with viral hepatitis, the RDW showed a positively linear correlation with TBi or PT and a negatively linear correlation with Alb, while the MCV showed a positively linear correlation with PT and a negatively linear correlation with Alb. Conclusion The parameters of RDW and MCV can simply reflect the damage of hepatic function of patient with viral hepatitis and has some clinic significance.更多还原