节点文献
桃仁总蛋白对荷瘤鼠T淋巴细胞亚群及细胞凋亡的影响
The Effects of PSP on the Subset of Tcell and Apoptosis of the Tumor-bearing Mice
【摘要】 目的 观察PSP对S180肉瘤小鼠T淋巴细胞亚群及肿瘤细胞凋亡的影响 ,并探讨其免疫调节及抗肿瘤的作用机制。方法 FACSCalibur流式细胞仪检测荷瘤鼠T淋巴细胞亚群及肿瘤细胞凋亡。结果 PSP能调节CD4 + /CD8+ 细胞的比例 ,诱导肿瘤细胞凋亡。结论 PSP可改善机体异常的免疫状态 ,调节免疫系统的失衡 ,并促进肿瘤细胞凋亡
【Abstract】 Objective To investigate the effect of PSP on subset of T cell and apoptosis of tumor cell from S180 cells mice and to study PSP the function of immunoregulation and the mechanism of antitumor.Methods The subset of T cell and apoptosis of tumor cell was detected by flow cytometer.Results That PSP could regulate the ratio of CD4 +/CD8 + cell, provoked the apoptosis of tumor cell. Conclusions PSP can improve abnormal state of immune, regulate the imbalance of immune function and promote the tumor cells’ apoptosis.
【关键词】 活血化瘀;
桃仁总蛋白;
免疫调节;
细胞凋亡;
【Key words】 Activating blood flow and removing blood stasis P.Persica (linn) batch seeds protein Immunoregulation Apoptosis;
【Key words】 Activating blood flow and removing blood stasis P.Persica (linn) batch seeds protein Immunoregulation Apoptosis;
【基金】 黑龙江省科委自然科学基金资助课题 (D0 0 - 1 7)一部分内容
- 【文献出处】 齐齐哈尔医学院学报 ,Journal of Qiqihar Medical , 编辑部邮箱 ,2004年05期
- 【分类号】R285
- 【被引频次】109
- 【下载频次】317