【摘要】 为了探讨黏膜无色素性恶性黑色素瘤 (简称恶黑 )的病理形态特点及误诊原因 ,对 9例初诊时误诊的黏膜无色素性恶黑进行光镜观察及免疫组化染色。 9例中发生于鼻腔 2例 ,宫颈 1例 ,阴道 2例 ,肛管直肠 3例 ,道格拉氏窝 1例。初诊分别误诊为浆细胞瘤、淋巴瘤、垂体瘤、鳞癌、平滑肌肉瘤、腺癌 ,后经免疫组化染色确诊。初步研究结果提示 ,黏膜恶黑比较少见 ,且形态复杂 ,经验不足或没有免疫组化标记非常容易误诊更多还原

【Abstract】 To study the pathological characteristics and misdiagnostic causes of mucosa-associated malignant melanomas,nine cases of misdiagnosed mucosa-associated malignant melanoma were studied by light microscope and immunohistochemistry.Nine cases of mucosa-associated malignant melanoma were 2 from rhinal cavity and 1 from cervix,2 from vagina,3 from anus and rectum,1 from Douglas cavity.At first,these cases were misdiagnosed as plasmacytoma,lymphma,squamos cell carcinoma,leiomyosarcoma and adnocarcinoma.At last,correct diagnosis were made by immunohistochemical staining.Mucoa-associated malignat melanoma is rare tumor and its morphology is various.Without experience and without the help of immuno staining,it is very easy to make misdiagnosis.更多还原