【摘要】 目的 :观察恶性肿瘤患者免疫功能治疗前后变化及血清可溶性白细胞介素 -2受体 (sIL 2R)表达。方法 :单克隆抗体法。结果 :1)恶性肿瘤患者各项免疫活性细胞表达均低于对照组 ;2 )恶性肿瘤患者血清sIL 2R表达显著高于对照组 ;3 )免疫功能与临床治疗效果成正比 ;4)血清sIL 2R表达与临床治疗效果成反比。结论 :恶性肿瘤患者T细胞亚群、NK细胞活性受到抑制 ,血清sIL 2R呈现高表达 ,对临床治疗及预后具有重要指导意义。更多还原

【Abstract】 OBJECTIVE:To observe the immuno function and expression of sIL 2R in serum of cancer patients.METHODS:The monocolonal antibody assay was used.RESULTS:1)The immuno expression in cancer patients was lower than that in normal subjects.2)The serum sIL 2R level in cancer patients was higher than that in the control.3)The treatment results were positive correlated with the immuno function.4)The treatment results were negatively correlated with serum sIL 2R level.CONCLUSIONS:T cell subgroup and NK acitivity are inhibited in the patients with malignant tumour.A high expression surum sIL 2R level is of important directive value to clinical treatment and prognosis.更多还原