【摘要】 目的 :探讨磁共振波谱 (magneticresonancespectrum ,MRS)检查对颞叶癫患者致灶的定位价值。方法 :对 36例颞叶癫患者进行MRS检查 ,主要分析波谱的三个峰 :N—乙酰天门冬氨酸 (NAA)峰位于 2 0 ppm ,总肌酸 (Cr)峰位于 3 0 ppm ,胆碱类物质 (Cho)峰位于 3 2ppm) ,根据波峰曲线下的绝对面积计算出NAA/ (Cr +Cho)的比值 ,以NAA(Cr +Cho) <0 6 8作为判断异常的标准。结果 :36例病人中 34例NAA/ (Cr+Cho)比值 <0 6 8,其中双侧异常 2 1例 ,单侧异常 13例。结论 :MRS能准确反映体内NAA、Cho、Cr等代谢产物的变化 ,对颞叶癫的致灶有定位价值。更多还原

【Abstract】 Objective:To explore the value of magnetic resonance spectrum (MRS) in the localization of epileptogenic focus in patients with temporal lobe epilepsy.Methods:Magnetic resonance spectrum was determined in 36 patients with temporal epilepsy.The three wave peaks of MRS were mainly analyzed,which included the NAA N acetylaspantate peak at the site of 2.0ppm,Cr Creating and phosphocr eatine peak at 3.0ppm and Cho peak at 3.2ppm.The ratio of NAA/(Cr+Cho)was worked out according to the absolute area auder the curve of the wave peaks and the ratio of NAA/(Cr+Cho) below 0.68 was regarded as a standard for judgement of abnormality.Results:The ratio of NAA/(Cr+Cho) was found below 0.68 in 34 patients out of 36 ones,including bilateral abnormality in 21 patients and unilateral abnormality in 13 ones.Conclusions:MRS might reflect accurately the changes of the metabolites such as NAA,Cho,Cr ect.It might be valuable in the localization of temporal epileptogenic focus.更多还原