【摘要】 目的 :探讨乙型肝炎病毒前 S1抗原 ( Pre S1 Ag)与乙型肝炎病毒血清标记物 ( HBV-M)、乙型肝炎病毒 DNA( HBV-DNA)的关系 ,以及与肝炎分型的关系。方法 :Pre S1 Ag测定使用酶联免疫吸附试验 ( ELISA)。结果 :2 0 9例 Pre S1 Ag阳性血清标本中 ,乙型肝炎表面抗原、乙型肝炎 e抗原、乙型肝炎核心抗体三者阳性者共84例 ,占 40 .1 9% ;乙型肝炎表面抗原、乙型肝炎 e抗体、乙型肝炎核心抗体三者阳性者 74例 ,占 3 5 .41 % ;二者合计 75 .60 %。Pre S1 Ag阳性与 HBV-DNA符合率 94.74%。结论 :Pre S1 Ag阳性与 HBV-DNA呈正相关性 ,是乙型肝炎病毒存在和复制的新标志更多还原

【Abstract】 Objective: To probe into relationship of HBV PreS1Ag and HBV-M or HBV-DNA, and hepatitis type. Methods: Test of PreS1Ag was by !ELISA". Results: In 209 cases of HBV PreS1Ag positive serum, !HBsAg(+), HBeAg(+), HBcAb(+)" has 84 cases, positive rate is 40.19%. !HBsAg(+), HBeAb(+), HBcAb(+)" has 74 cases, positive rate is 35.41%. Total positive rate is 75.60%. It is 94.74% that PreS1Ag to HBV-DNA conformed. Conclusion: It has positive correlation between PreS1Ag(+) and HBV-DNA(+). PreS1Ag is a new marker of HBV survival and replication.更多还原