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HPLC法测定滑膜炎颗粒中原儿茶醛的含量

Determination of Content of Protocatechualdehyde in Huamoyan Granule with HPLC Method

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【作者】 李丹赵新慧潘扬蔡宝昌葛冬

【Author】 LI Dan 1, ZHAO Xin-hui 2, PAN Yang 2, CAI Bao-chang 3, GE Dong 4 ( 1Nanjing Municipal Drug Inspection Station, Nanjing, Jiangsu,210025; 2Jiangsu Zhongkang New Drug and Fingerprint Chromatography Development Company Ltd., Nanjing, Jiangsu,210029,China; 3Nanjing University of Traditional Chinese Medicine, Nanjing Jiangsu,210029,China; 4Fire Department Hospital for Armed Police, Nanjing, Jiangsu,210008,China)

【机构】 南京市药品检验所江苏中康新药指纹图谱开发有限公司南京中医药大学武警江苏省消防总队医院 江苏南京210025江苏南京210029江苏南京210008

【摘要】 目的 建立滑膜炎颗粒剂中原儿茶醛的含量测定方法质量。方法 采用高效液相色谱法对方中原儿茶醛进行含量测定。结果 高效液相色谱法测定结果表明原儿茶醛在 0 .10 0 5~ 1.0 0 5 μg范围内呈线性关系 ,平均加样回收率为99 .2 2 % ;RSD为 0 .72 %。结论 本法简便 ,重现性好、结果可靠 ,可作为控制滑膜炎颗粒剂的质量方法

【Abstract】 OBJECTIVE To establish determination method for the content of protocatechualdehyde in Huamoyan Granule.METHOD High performance liquid chromatography was used to determine the content of protocatechualdehyde in Huamoyan Granule.RESULT The result of high performance liquid chromatography determination suggested that within the range of 0.001 5~1.005 μg, protocatechualdehyde assumed linear correlation, the average sample recovery rate was 99.22% and RSD was 0.72%.CONCLUSION This method is simple and reliable with good reproducibility, and therefore can be used in the quality control for Huamoyan Granule.

  • 【文献出处】 南京中医药大学学报 ,JOURNAL OF NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE , 编辑部邮箱 ,2004年04期
  • 【分类号】R286
  • 【下载频次】130
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