【摘要】 目的　考察无机陶瓷膜在清络通痹水提液精制过程中 ,不同孔径的膜对该体系的适用性 ,药液温度、流速及操作压力等工艺参数对膜过程的影响及膜分离操作终点判定 ,进行膜过程优化设计。方法　以清络通痹水提液为研究对象 ,测定了 3种不同孔径膜及不同操作参数下膜通量的变化、有效成分含量及固形物含量等。结果　对于本体系 ,孔径为 0 .2μm的氧化铝膜渗透通量最大 ,固形物去除率高 ;合适的操作压差为 0 .15～ 0 .2 0MPa ,操作温度 6 0℃左右 ,膜面流速3m s;微滤过程中 ,分次加入适量水洗 ,当微滤液收率达到原药液的 10 0 %以上时 ,有效成分转移率达 80 % ,即可结束微滤。结论　采用 0 .2 μm的氧化铝膜对清络通痹水提液进行微滤 ,在适当操作条件下可取得较好精制效果 ,为陶瓷膜分离用于中药精制领域的共性问题提供了依据更多还原

【Abstract】 OBJECTIVE To observe the effect of different inorganic pottery membranes on the parameters of techniques so as to optimize the process of production of Qingluo Tongbi Granule. METHOD Three different membranes were tested under different parameters of operation to observe changes in membrane flux and the content of effective components and solids. RESULT For the main body, the oxidized aluminum membrane with the 0.2 μm aperture had the greatest permeation flux with the highest rate of solid removal; the appropriate operation differential pressure was 0.15～0.20 MPa; the operation temperature was around 60℃; the membrane surface flow rate was 3 m/s. When the microfiltrate reached 100% of the original liquid and the effective transfer rate reached 80%, the microfiltration was finished. CONCLUSION By adopting 0.2 μm oxidized aluminum membrane in the microfiltration of Qingluo Tongbi Liquid, good result can be obtained. This provide basis for the application of pottery membrane isolation to the refinement of Chinese drugs.更多还原