【摘要】 果蝇已成为研究昆虫和人类天然免疫的重要模式生物,它主要是通过体液免疫和细胞免疫来抵抗各种病原微生物的侵染。研究表明,果蝇的免疫基因表达主要受两种信号转导途径的调控,即Toll/dif途径和Imd/relish途径。本文主要就果蝇的天然免疫特征和免疫中的信号转导途径进行了综述。更多还原

【Abstract】 Drosophila has become the important model for the study of the innate immunity of insect and human. Its defense against invading pathogens includes humoral and cellular reactions. The immune gene expression of Drosophila is regulated by two signal transduction pathways: toll/dif and imd/relish. The characteristics of the innate immunity of Drosophila and the mechanisms of the signal transduction pathways are discussed in this review.更多还原