【摘要】 目的 :　了解麻风无痛性神经炎在各型及实施MDT治疗的不同时期的发生情况。方法 :　定时测试周围神经的感觉和运动功能 ,前后对照 ,以发现早期无痛性神经炎。结果 :　观察 4 5 6例MDT治疗期 ,监测期及解除监测期患者 ,发现无痛性神经炎 4 8例 ,累计检出率 10 .5 3%。治疗期患者的发生率明显高于监测期及解除监测期患者 (P <0 .0 1) ,尺神经和胫神经检出率明显高于其它神经 (P <0 .0 1)。结论 :定期检测周围神经功能 ,早期发现无痛性神经炎十分重要更多还原

【Abstract】 Objective: To determine the incidence rate of silent neuritis in leprosy under MDT, post-MDT follow-up and released from control (RFC).Methods: The sensory and motor function of peripheral nerves at regular intervals was examined in three cohorts of leprosy patients.Results: Total 456 leprosy cases under MDT, post-MDT and RFC were recruited. During a maximum of 24 months 48 cases of silent neuritis were detected with an incidence rate 10.53%. The detection rate of cases under MDT was significantly higher than that in patients of post-MDT and RFC (P<0.01). The most common involved nerves were ulnar and tibial nerves. The detection rate for the two nerves was higher than that in other nerves (P<0.01). Conclusion: It is important that early detection of silent neuritis by examining function of peripheral nerve at regular intervals.更多还原