【摘要】 目的　探讨乳头状汗管囊腺瘤 (SCAP)的临床病理特征和诊断要点。方法　分析 5例SCAP临床资料 ,观察其组织学形态及免疫表型特征。结果　本组男 4例、女 1例 ;发病年龄 0～ 14岁 ,临床上皮损表现为数个丘疹呈线状排列或孤立性结节、斑块。组织学特征 :大小不一的乳头状突起衬以两层上皮细胞。免疫表型 :SCAP绝大多数内层柱状细胞CK7、CK19阳性 ,外层立方细胞CK5 / 8、CK7阳性。结论　SCAP是一种少见的良性皮肤错构瘤 ,鉴别诊断包括乳头状汗腺囊腺瘤、管状大汗腺腺瘤。更多还原

【Abstract】 Purpose To explore the clinicopathological features and diagnosis of syringocystadenoma papilliferum(SCAP). Methods Five cases of CSAP were analyzed by means of clinicopathologic date,histopathologic features,immunohistochemical technique. Results There were four males and one female, with age ranged 0～14 years. Clinically,the lesions of the skin consisted of one to several papules occurring in a liner fasion or as a solitary nodule and plaque. Microscopically, the distinctive feature was the presence of papillary processes of various sizes lined with two epithelial cell layers. Immumohistochemically, the columnar cells of the tumour were mostly positive for CK7 and CK19. The cuboidal cells of the tumor expressed CK5/8 and CK7. Conclusions SCAP is a rare benign hamartomatous tumour of the skin.The differential diagnosis of SCAP includes hidradenoma papilliferum and tubular apocrine adenoma.更多还原