【摘要】 目的 :报告 1例皮肌炎、硬皮病重叠综合征。患者男性 ,1 4岁 ,反复四肢乏力 5年余 ,左下肢红斑萎缩 2年。肌电图示右肱二头、左股直肌、右三角肌肌源性损害 ;肌活检镜下示肌肉结构基本正常 ,仅见少数肌纤维萎缩 ,间质可见明显炎症病变 ;左下肢皮肤红斑活检镜下示轻度角化过度 ,表皮变薄 ,真皮胶原增厚、增粗 ,附件减少 ,血管周围轻微炎症细胞浸润更多还原

【Abstract】 Objective:We report a case with sclerodermatomyositis in the paper. Famele case, 14 years old, progressive weakness for 4 years. Erythroma with atrophy on the left leg for 2 years. Electromyogram of right lamb and left leg demonstrated myopathy. The histologic changes were showed thining of epidermis, hydropic degeneration of the basal layer, edema in the papillary dermis, and a perivascular lymphocytic infiltrate in the superficial and deep dermis. The laboratory findings were confirmed the diagnosis of sclerodermatomyositis.[更多还原