【摘要】 目的 :探讨脉压指数与冠状动脉病变严重程度的关系。方法 :82 0例均经冠状动脉造影检查 ,外周肱动脉压力测定收缩压 (SBP)、舒张压 (DBP) ,冠状动脉病变的严重程度用冠状动脉病变的血管支数表示。分别以脉压≤ 6 0mmHg(1mmHg =0 .133kPa)、>6 0～ 80mmHg、>80～ 10 0mmHg及 >10 0mmHg和脉压指数≤0 .4 0 0、>0 .4 0 0～ 0 .5 0 0、>0 .5 0 0～ 0 .6 0 0、 >0 .6 0 0 4个组进行分析。结果 :随着脉压和脉压指数的增加 ,冠心病患病率均随之增加 (P <0 .0 5 ) ,年龄呈增大趋势 ,双支和 3支冠状动脉病变患病率显著增高。Logistic回归分析 ,年龄、脉压、脉压指数对冠状动脉病变有最好的预测价值。结论 :脉压和脉压指数是最为方便的反映大动脉弹性的参数 ,与冠状动脉病变的严重程度密切相关 ,脉压指数比脉压在预测心血管事件危险性方面具有一定的优越性更多还原

【Abstract】 Objective:To investigate the relationship between pulse pressure index(PPI) and coronary artery lesions. Method: A total of 820 elderly patients were divided into 4 groups according to the level of pulse pressure(PP) [≤60 mmHg(1 mmHg= 0.133 kPa),61～80 mmHg, 81～100 mmHg and>100 mmHg]and PPI (≤ 0.400, 0.401～ 0.500, 0.501～ 0.600 and > 0.600). Brachial systolic and diastolic blood pressure were measured.The severity of coronary heart disease was indicated as the number of diseased arteries. Result:As PPI and PP increased,the incidance of coronary heart disease and ≥2 coronary artery disease went higher and age increased.In a multivariate analysis,age, PPI and PP were the best predictors for the severity of coronary lesions. Conclusion: PPI and PP are the simpliest paranmeter reflecting large artery elasticity and closely related to severity of coronary artery disease. PPI is better than PP in elderly patients.更多还原