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阴囊Paget病的诊断与治疗(附64例分析)

Diagnosis and treatment of extramammary Paget’s disease of the scrotum:a report of 64 cases

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【作者】 吴正沐丁强张元芳姜昊文童仕俊

【Author】 WU Zhengmu 1 Ding Qiang 1 ZHANG Yuanfang 1 JIANG Haowen 1 TONG Shijun 1 ( 1Department of Urology, Huashan Hospital of Fudan University, Shanghai,200040, China)

【机构】 复旦大学附属华山医院泌尿外科复旦大学附属华山医院泌尿外科 上海200040上海200040上海200040

【摘要】 目的:探讨有关阴囊Paget病的临床特点、预后因素和手术处理原则,提高外科医生对阴囊Paget病 的认识。方法:回顾性分析我院1993~2003年收治的64例阴囊Paget病患者的临床资料。结果:104例患者平 均年龄68岁,从初发症状到明确诊断的间隔时间平均为2年9个月。除1例采用激光治疗外,其余均采用手术 病灶切除术,术后皮肤结构重建,效果满意。术后局部复发8例,其中与该病相关死亡3例。结论:阴囊Paget病 容易漏诊,发现阴囊、会阴附近部位皮肤出现可疑的湿疹样病变,应尽早行皮肤活检。早期彻底切除病灶能减少 局部复发。

【Abstract】 Objective:To review the diagnosis and treatment of extramammary Paget’s disease of the scrotum.Methods:Clinical data of 64 patients with extramammary Paget’s disease involving the scrotum were analysed.Results:The median age of 104 patients was 68 years. The median duration of symptoms before treatment was 2 years and 9 months. Therapeutic modalities included carbon dioxide laser ablation (1 case) and local wide excision (63 cases). Recurrence occurred in 8 cases and regional lymph node metastasis in one case.Three patients died of the disease.Conclusions:Histological examination should be done for doubtful cases.The prognosis is good for operative cases.

【关键词】 阴囊Paget病诊断治疗
【Key words】 Paget’s disease of scrotumDiagnosisTheraputics
  • 【文献出处】 临床泌尿外科杂志 ,Journal of Clinical Urology , 编辑部邮箱 ,2004年12期
  • 【分类号】R697
  • 【被引频次】7
  • 【下载频次】217
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