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自体肾移植治疗输尿管癌的探讨
Renal autotransplantation for upper tract urothelial tumors
【摘要】 目的 :探讨输尿管癌自体肾移植治疗的理论基础和优点。方法 :对 9例输尿管癌患者行自体肾移植术治疗 ,切除输尿管癌上方 3cm正常输尿管及下方输尿管全长 ,并做膀胱输尿管入口处的袖套状切除术 ;患侧肾行同侧髂窝肾移植、输尿管膀胱再吻合术。结果 :9例输尿管癌包括T3 4例和T2 4例中 ,各有 1例膀胱癌复发 ,其余无尿路上皮肿瘤复发 ,其生存率 1年为 10 0 % ,2年为 88.8% ,5年为 6 6 .7%。结论 :自体肾移植术对输尿管癌患者的治疗效果基本等同于传统的根治性肾输尿管切除术 (包括膀胱袖套状切除 ) ,对于孤立肾及双肾功能不良的患者也是个好的手术方式 ,为以往不能行保留肾功能的高分期孤立肾及双肾功能不良的输尿管癌患者争取到手术机会。为输尿管上段肿瘤患者也提供了一个可选择的保肾手术方式。
【Abstract】 Objective:To study the rationale and advantage of the Renal autotransplantation for the treatment of the upper urinary tract urothelial tumors.Method:The renal autotransplantation had performed in 9 cases of upper tract urothelial tumors, all ureter from 3cm above the ureteral neoplasms to ureter orifice were removed in the operation and with a excision of a cuff of bladder; the removed renal were autotransplantated to ipsilateral iliac fossa.Result:There were 2 cases recurranted in bladder in 5 year fellow-up, the 1 , 2, 5 yeas survival rate were 100% (9/9), 88.8% (8/9) and 66.7% (6/9), respectively.Conclusion:The Renal transplantation has the same therapeutic effect as the total nephroureterectomy (with a excision of a cuff of bladder) for the upper tract urothelial tumors. It’s a valuable choice for the ureteral carcinoma patients who has unitesticle or renal failure, and also is a good means to save kidney for proximal ureteral tumor’s patient.
【Key words】 Autotransplantation; Ureteral neoplasm; Transitional cell carcinoma;
- 【文献出处】 临床泌尿外科杂志 ,Journal of Clinical Urology , 编辑部邮箱 ,2004年04期
- 【分类号】R737.13
- 【被引频次】2
- 【下载频次】64