【摘要】 目的 :探讨哈伯因对精神分裂症患者记忆功能障碍的疗效。　方法 :80例首发精神分裂症患者平分为哈伯因合并奎硫平治疗 (合用组 )和单用奎硫平治疗 (单用组 ) ,疗程 8周。采用阳性与阴性症状量表 (PANSS)、韦氏记忆量表修订版 (WMS RC)评定精神症状及记忆功能 ,分别于治疗前、治疗 8周各评定 1次。　结果 :治疗后两组患者记忆功能损害和精神症状均获得显著改善 ,两组间无显著差异 ,记忆功能的改善与精神症状的改善相关。　结论 :哈伯因对精神分裂症的记忆功能障碍疗效不明显更多还原

【Abstract】 Objective:To observe the clinical efficacy of hyperzine on memory function in patients with first-episode schizophrenia. Method:Eighty first-episode schizophrenia were randomly divided into with quetiapine and hyperzine(study group) and only with quetiapine(control group) for 8 weeks.The memory function was evaluated with WMS-RC,and the mental symptoms were assessed with PANSS before and at the end of the treatment. Results:The scores of WMS-RC increased markedly,while the scores of PANSS decreased markedly in both groups.There was postive correlation between the improvement of memory function and mental symptoms in each group,but no significant difference was found between two groups. Conclusion:Hyperzine may be no significant efficacy on improving the memory function in the first-episode schizophrenia.更多还原