Objective:To explore the relationship between the treatment and the T102C polymorphisms of 5-HT 2A receptor gene in Han peoples with refractory depression. Method:The genotype and allelomorph of 5-HT 2A receptor gene in blood cell were examined with PCR-RFLP in 79 refractory depression patients and 102 controls respectively. Results:The frequencies of three T102C genotype of 5-HT 2A receptor gene (A1/A1,A1/A2 and A2/A2) were 31.6%, 54.4% and 13.9% respectively in the patients and 29.4%,45.1...