【摘要】 目的 :探讨丁螺环酮与氟西汀联合治疗抑郁症的疗效。　方法 :抑郁症患者 6 5例 ,随机分成两组 ,分别用丁螺环酮联合氟西汀治疗 (联用组 )和单用氟西汀治疗 (单用组 ) ,疗程 6周。采用汉密顿抑郁量表 (HAMD)、汉密顿焦虑量表 (HAMA)评定疗效 ,用不良反应量表 (TESS)评定不良反应。　结果 :治疗 6周后联用组HAMD和HAMA评分显著低于单用组 ;在第 2、第 6周末联用组的治疗有效率显著高于单用组。两组不良反应相仿。　结论 :丁螺环酮联合氟西汀治疗抑郁症有良好的疗效更多还原

【Abstract】 Objective:To explore the clinical efficacy of combined buspirone and fluoxetine in the treatment of major depression. Method:65 patients with major depression were involved in this study, they were randomly assigned to two groups (buspirone with fluoxetine or fluoxetine alone) for 6 weeks.Efficacy and side effect were assessed with Hamilton depression rating scale (HAMD),Hamilton anxiety scale (HAMA) and treatment emergent symptom scale (TESS) before and after the treatment. Results:Total HAMD, HAMA scores decreased significantly more in buspirone-fluoxetine group than in fluoxetine group,but there was no significant difference in TESS. Conclusion:Buspirone-fluoxetine is a highly effective treatment for major depression.更多还原