【摘要】 杨树(PopulussimoniiCarr.)皮提取物经皂化、萃取、分离和精制,能够得到30%～36%的不饱和脂肪酸乙酯产品。该产品经气相色谱分析,共分离出22个色谱峰,鉴定出21个化合物,其中主要的不饱和脂肪酸乙酯成分为亚油酸乙酯,含量高达94.04%。已鉴定的组分占产品总量的99.19%,其中不饱和脂肪酸酯占95.94%,饱和脂肪酸酯占3.14%。药效试验证明,杨树皮不饱和脂肪酸乙酯产品能显著降低试验性高脂血症大鼠的血清总胆固醇(TC)、甘油三脂(TG)和低密度脂蛋白的胆固醇(LDL-C)水平(P<0.001),而对血清中高密度脂蛋白的胆固醇(HDL-C)含量有升高作用。更多还原

【Abstract】 Unsaturated fatty acid ethyl ester product was obtained from poplar bark extract through saponification,(extraction),separation and purification,at yield 30%-36% of the extract.It consists of 95.94% esters of unsaturated fatty acid and 3.14% esters of saturated fatty acid.This product is analysed by GC.Of the 22 peaks,21 components which make up (99.19%) of the total weight were identified.The major component is linoleic acid whose content reached 94.04%.Medicine effectiveness test of the product showed that TC,TG and LDL-C in serum of high blood-(lipoid) rats(P<0.001) can be reduced obviously and content of HDL-C in serum is increased.更多还原