【摘要】 目的 :探讨混合氧联合药物治疗突发性聋的临床疗效及其可能的治疗机制。方法 :将 5 2例突发性聋患者随机分为混合氧联合药物治疗与单纯药物治疗两组 ,各 2 6例。混合氧治疗为常压下吸入 5 %CO2 和 95 %O2 的混和气体 ,每次吸入 30min后休息 30min ,然后再吸入 30min ,每日如此循环 2次 ,配合使用类固醇激素及扩血管营养神经药物 ;对照组单纯使用上述同类药物治疗 ;比较两组疗效。结果 :治疗组总有效率 76 .9% ,听力开始恢复时间在治疗后 3～ 14d ;对照组总有效率 5 0 .0 % ,听力开始恢复时间在治疗后 6～ 2 3d ,两组总有效率差异有统计学意义 (P <0 .0 5 ) ,听力开始恢复时间差异无统计学意义。结论 :混合氧联合药物治疗突发性聋疗效优于单纯药物治疗更多还原

【Abstract】 Objective:To analyze the clinical efficiency and study the possible mechanism of the carbogen combined with drugs in the treatment of sudden deafness.Method:Fifty-two patients with sudden deafness were divided into two groups:Twenty-six cases received carbogen(5%CO 2-95%O 2) combined with drug therapeutics of a course of intravenous administration of dexamethasone,vitaminB, low molecular dextran, salviae miltiorrhizae, and intake vitaminC, vitaminE,et al and the other 26 cases received the drugs only. The clinical effects were compared.Result:The total effective rate was 76.92% in the carbogen group and 50.00% in the control group.The difference was significant between the two groups.The recovery time in the carbogen group was 3～14 days while in the control group was 6～23 days.Conclusion:The efficiency of carbogen ombined with drugs is superior to drug therapeutics in the treatment of sudden deafness.更多还原