【摘要】 目的 :探讨自控吸入笑气镇痛技术用于人工流产术的效果。方法 :将 1 6 4例孕妇随机分为实验组 (n =80 )和对照组 (n =84 )。实验组患者在术前 2min自控吸入笑气至手术束 ,对照组患者术前静脉注射氯胺酮 0 .4mg/kg、阿托品 0 .5mg和安定 5mg。观察比较各组术前、术中的血压、心率、呼吸、脉搏、血氧饱和度和镇痛麻醉效果 ,以及子收缩、手术时间、出血量和患者术后神志清醒所需时间。结果 :比较 2组血压、心率、子宫收缩、手术时间、出血量、副作用和镇痛麻醉效果 ,结果无显著差异 (P >0 .0 5 )。对照组患者术中呼吸频率 (2 0 .0 6± 1 .5 0 )和脉搏血氧饱和度 (97.6 5± 1 .5 7)均低于术前 ,相比有显著差异 ,(t =2 .6 36 ,P <0 .0 1 ;t =5 .6 7,P <0 .0 1 )。同时对照组患者术中脉搏血氧饱和度低于实验组 (98.5 8± 1 .38) ,相比有显著差异 (t=4 .0 4 ,P <0 .0 1 )。结论 :自控吸入笑气镇痛技术安全可靠、使用简单方便 ,可以满足人工流产术中镇痛的需求更多还原

【Abstract】 Objective: To study the analgesic effects of inhaling laughing gas with BPCA in induced abortion. Methods: 164 cases of induced abortion were randomly divided into the observational group (n=80) and the control group (n=84). Patients in the observational group were given laughing gas with BPCA from two minutes ahead of operation to the end, and those in the control group were administrated ketamine 0.4mg/kg, atropine 5mg and diazepam 0.5mg before operation. BP, HR, R, S pO 2, the degree of pains and anesthetic effects before and during induced abortion, the contraction of uterine, operating time, the amount of hemorrhage and the time needed to restore to right senses after operation were observed and compared between two groups. Results: There was no significant difference in BP, HR, the contraction of uterine, the operating time, the bleeding amount, the adverse effects, the degree of pains and the anesthetic effects between two groups( P >0.05). R (20.06±1.50)and S pO 2(97.65±1.57) in control group were significantly less during induced abortion than that of prior to induced abortion ( t=2.636,P<0.01;t=5.67,P <0.01),and S pO 2 in the control group was also significantly less than that of the observational group(98.58±1.38),( t=4.04,P <0.01). Conclusion: Inhaling laughing gas with BPCA can be used effectively and safely during induced abortion.更多还原