【摘要】 目的 评价含二氧化氯的口腔消毒剂的体内消毒效果。方法 采用现场实验的方法,唾液采样,观察口腔消毒剂使用前后口腔细菌的改变。结果 对照组使用蒸馏水漱口后总菌数及各菌数均有减少,但差异无显著性。实验组使用二氧化氯漱口后即刻、漱口后 lh 10min的总菌数、链球菌数和第一种球菌数均有下降,其中漱口后即刻总菌数下降最低,到漱口后 lh 40min总菌数、链球菌数恢复,但第一种球菌数仍未恢复漱口前水平。其它变化差异无显著性。结论 含二氧化氯的口腔消毒剂对口腔细菌包括可疑致病的革兰氏阳性和阴性菌,需氧菌和厌氧菌的链球菌、球菌均有明显杀灭、抑制作用,并可维持一定时间。更多还原

【Abstract】 Objective To study the inhibition potential of a chlorine dioxide-containing oral rinse formulation invivo. Methods The ability of an oral rinse preparation containing an admixture of the chlorine dioxide to diminishsalivary levels of oral bacteria was investigated in a group of 15 dental student volunteers. A group of 15 dental studentvolunteers, who used distilled water, served as the control group. Salivary microorganism levels were determined prior andsubsequent to the period. Results The results demonstrated that the oral rinse formulation tested gave rise to asubstantial reduction in salivary Streptococcus and Staphylococcus levels after rising shortly and after one hour and tenminutes (P<0.001 and 0.01, respectively), although the decrease observed in one hour and forty failed to reach statisticalsignificance. As expected, distilled water employed as an oral rinsing system by the student control group, exerted noinfluence on the salivary levels of each of these microorganisms. Conclusion Chlorine dioxide containing oral rinseformulation is efficacious for the inhibition of oral bacteria.更多还原