社区督导肺结核病人化疗药物副反应分析

【摘要】 目的　了解社区督导肺结核病人应用短程化疗方案药物副反应 ,指导规范化用药。方法　对实施河南省加强与促进结核病控制项目 (方案 1)和世界银行贷款 /英国赠款结核病控制项目 (方案 2 )的部分项目县及其项目化疗病人的药物副反应进行调查分析。结果　药物副反应发生率两方案分别为 2 8.3%和 2 9.5 % ,其中最常见的胃肠反应分别为 2 0 .1%和 2 1.0 % ,因胃肠反应停药率分别为 4 .5 %和 7.8% ,副反应随年龄增加成正相关 ,女性病人中明显增多 ;药物副反应对病人治疗效果有明显影响。结论　应加强对社区督导服药病人的化疗药物副反应观察、监测和及时处理 ,以规范化治疗 ,保证国家规划目标的实现更多还原

【Abstract】 Objective To understand the short-term chemotherapy side effect of pulmonary tuberculosis withcommunity surveillance and instruct standardized chemotherapy. Methods To investigate and analysis the chemotherapy side effect of patients withimplemention HeNan TB Control Project (programme 1)and world Bank loaned/Britain Grant TBControl Project (programme 2). Results Occurance rate of drug side effects are 28.7%and 28.3% respectively, of which the most common digestive side effects are 20.5% and 21.0% and the stopping drug rate are 4.5% and 7.8% respectively.Side effects have direct correlation as increasing age always happen in female patients and influence the treatment outcome obviously.Conclusion To realize natial project aims and complete standardization chemotherapy, theobservation of drug side effect, monitoring and prompt treatment with community surveillancepatients should be strengthened.更多还原