【摘要】 目的 :旨在探讨胰岛素和噻唑烷二酮合用在糖尿病的强化治疗中利弊。方法 :患者随机分为胰岛素组(对照组 )和胰岛素 +噻唑烷二酮 (文迪雅 )组 (实验组 ) ,观察用药后指标变化。结果 :治疗 12周实验组与对照组于治疗前比较FPG ,2h -PPG ,Wg有显著性差异 (p <0 0 5 )。治疗 12周后实验组与对照组相比 ,对FPG ,2h -PPG ,Wg的影响有显著性差异 (p <0 0 5 )。结论 :两组均可较好控制血糖 ,实验组效果更好 ,但体重增加明显 (p<0 .0 5 )更多还原

【Abstract】 Objective: we want to evaluate benefits and defect which caused by thiazolidinediones and insulin in combination extensive therapy. Research design and methods: patients were divided into insulin group and combination group randomly, we studied changes over 12 weeks. Outcome measures included HBA1C, FPG, 2h-PPG, weight. Results: two groups also have statistical and significant change in HBA1C, FPG, 2h-PPG, weight, before and after therapy. At the same time, two group are different in weight, FPG, and 2h-PPG significantly. Conclusions: two group also can control glucose level well, combination group and better in effection but worse in weight than insulin group.更多还原