【摘要】 目的 :研究慢性阻塞性肺病急性发作期伴与不伴肺炎的特点 ,以及各自的治疗效果 ,探讨慢性阻塞性肺病社区治疗的可能性。方法 :已确诊的慢性阻塞性肺病急性发作期患者 ,经X线检查 ,被分成肺炎组 12例 ,非肺炎组 2 2例。两组患者均进行血常规 ,血气分析 ,痰培养 +药敏 6次 (治疗前及治疗后各 3次 )及治疗前后茶碱浓度测定。患者治疗均使用氧氟沙星及氨茶碱和止咳化痰药物。结果 :伴与不伴肺炎比较 :发热、白细胞增高例数、PaO2 、住院例数、细菌培养阳性率、混合感染例数均有显著性差异。两组治疗前后血茶碱浓度均在正常范围。结论 :慢性阻塞性肺病社区获得性肺炎较为常见 ,通常其临床表现、实验室检查较不伴肺炎者为重 ,通过治疗比较 ,伴肺炎者在社区治疗要密切观察 ,且使用氧氟沙星 +氨茶碱治疗 ,茶碱浓度是安全的 ,对指导社区慢性阻塞性肺病的治疗有一定意义。更多还原

【Abstract】 purpose: We discuss characters and treatment effect in acute COPD with or without pneumonia and explore the possibilities of the treatment in community. Method: We divided patients who were diagnosed as acute COPD by X-ray into two groups. Pneumonia group(12 patients) and no-pneumonia group(22 patients). Two groups also received blood routine examination, Blood-das analysis, Sputum bacteria’s specified test 6 times. Before and after treatment, all patients also take ofloxacin, aminophylline and relieve cough-melt sputum drugs. Results: The results (fever, WBC, PaO2, admission times, positive of bacterial culture, mixed infection patients) have significant difference. Theocin consistence is normal before and after treatment in two groups. Conclusion: Pneumonia is usual in COPD, it’s worse than no-pneumonia COPD in laboratory test and clinic signs. The former needs serious observation and treatment with ofloxacin and aminophylline, theocin consistence is normal and safe. The conclusion is significant for treatment of COPD in community.更多还原