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肝癌患者血清假(拟)胆碱酯酶的测定及其临床意义

Detection of pseudocholinesterase in patients with liver cancer and its clinical significance

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【作者】 赵华刘琴王珏邹学森刘纬星

【Author】 Zhao Hua, Liu Weixing, Liu Qin, et al Clinical laboratory of jiangxi cancer hospital, Nanchang, 330029, China

【机构】 江西省肿瘤医院江西医学院核医学研究室 南昌 330029南昌 330029南昌 330006

【摘要】 目的 探讨肝癌患者血清假(拟)胆碱酯酶(PCHE)活力的变化及其临床意义。方法 采用速率法(双试剂)测定140例原发性肝癌,其中20例转移癌,同时测定白蛋白和总胆汁酸。结果 肝癌组PCHE、ALB均比对照组显著降低,TBA比对照组显著增高。且PCHE与ALB呈正相关,与TBA呈负相关。结论 血清PCHE是反映肝癌患者肝细胞功能受损程度的敏感指标。

【Abstract】 Objective To investigate the change and clinical significance of serum activity of pseudocholinesterase(PCHE) in patients with liver cancer. Methods Activity of PCHE were detected with Dual-reagent (rate technique) method in 140 patients with primary liver cancer, simultaneously serum concentration of ALB and TBA were measured. Rusults The activity of aerum PCHE and the levels of ALB were singificantly lower in the patients than in the control, the TBA significantly higher. There was negative correlation between the decrease of PCHE and TBA, while positive correlation between PCHE and ALB. Conclution Serum PCHE is sensitive index to reflect damage of liver cell functions in patients with liver cancer.

【关键词】 假(拟)胆碱酯酶肝癌
【Key words】 pseudocholinesteraseprimary liver cancer
  • 【文献出处】 江西医药 ,Jiangxi Medical Journal , 编辑部邮箱 ,2004年03期
  • 【分类号】R735.704
  • 【下载频次】53
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