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新型促渗剂噻酮

A New Skin Penetration Promoter: Thiazone

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【作者】 熊丽曾;

【Author】 XIONG Li-zeng (Institute of Applied Chemistry, Beijing Normal University,Beijing 100875,China)

【机构】 北京师范大学应用化学研究所 北京100875;

【摘要】 介绍了新型促渗剂噻酮的结构和物性 ,并通过其对小檗碱、环吡酮胺和氯氰菊酯的促渗效果实验 ,证明了噻酮的促渗效果好于目前广泛应用的促渗剂氮酮 ,促渗效果为氮酮的 2 99倍。同时还简介了噻酮的药检试验结果及其促渗机理。最后详细讲述了噻酮在医药、化妆品和保健品、农林和所有植物保护以及其他工业领域的广泛应用。

【Abstract】 Benzisothiazol-3(2H)-one-2-butyl-1,1-dioxide(THIAZONE) is a new skin penetration enhancer, the structure and physical properties of THIAZONE are introduced. Through the tests of penetration enhancing behaviors to berberine, ciclopirox olamino,cypermethrin, the results are proved that penetration enhancing effect of THIAZONE is higher than AZONE, about 2 99 times better than that of AZONE. Meanwhile, the results of medication examination and penetration enhancing mechanism for THIAZONE are narrated briefly. Finally, the wide application of THIAZONE in pharmaceutic industry, cosmetic and health care industry, agriculture and forestry industry, plant protection and other industries are introduced in detail.

  • 【文献出处】 精细与专用化学品 ,Fine and Specialty Chemicals , 编辑部邮箱 ,2004年21期
  • 【分类号】TQ463
  • 【被引频次】24
  • 【下载频次】401
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