【摘要】 3位取代的苯酞类化合物具有广泛的生理活性 ,通过一个新的简便合成路线高收率的得到了 3位取代苯酞衍生物。新工艺中最重要的一步反应是 3 乙氧基苯酞与丙二酸二乙酯的缩合 ,也是与Trost等人的合成路线主要的不同之处。更多还原

【Abstract】 Substituted phthalide derivatives possess a wide range of physiological activities. A new synthetic method has developed for its preparation. In this process the important reaction step is the condensation of 3-ethoxyphthalide with diethylmalonate, which mainly differs from Trost’s route.更多还原