【摘要】 目的　比较多虑平与阿普唑仑治疗广泛性焦虑症的疗效和不良反应。方法　采用与阿普唑仑的随机对照方法 ,将符合广泛性焦虑诊断标准的患者 72例 ,随机分为多虑平组 ( 3 6例 )和阿普唑仑组 ( 3 6例 )治疗 4周。用汉密尔顿焦虑量表 ,Zung焦虑自评量表 ,临床总体印象量表及临床疗效和治疗药物副作用量表评定疗效和药物的不良反应。结果　多虑平与阿普唑仑的疗效相近。多虑平对精神性焦虑症状的起效时间较阿普唑仑稍慢 ,对焦虑症状的治疗具有选择性 ,适用于门诊治疗。多虑平主要不良反应是轻微的口干、头昏。结论　多虑平治疗焦虑症有效 ,副作用较轻更多还原

【Abstract】 Objective To compare with the efficacy and side effects of dorepine and alprazolam in treatment of general anxiety disorder.Methods 72 cases who met with the criteria of CCMD-3 for general anxiety disorder were randomly assigned to dorepine group (36 cases)and alprazolarm group (36 cases)treatment for 4 weeks.Efficacy and side effects were evaluated with HAMD,SAS,CGI and TESS.Results Both drugs had similar efficacy in treatment of general anxiety disorder.Dorepine in treatment of psychotic anxiety symptoms was lowed than that of alprazolam.It has selectivity in treatment of anxiety symptoms.Conclusion Dorepine is efficient and safe in the treatment of general anxiety disorder.更多还原