【摘要】 以小鼠S180腹水瘤为动物实验模型 ,对氦氖激光照射与化疗药物环磷酰胺 (CYT)联合应用对S180荷瘤鼠外周血IgG含量影响作了系统性研究。应用 11 0 0 ,14 6 7和 2 2 0 0J/cm2 三种剂量氦氖激光照射荷瘤鼠内眼角 ,同时联合应用化疗药物环磷酰胺 ,动态监测S180荷瘤鼠外周血IgG含量的变化。结果表明 ,CYT联合应用氦氖激光照射组IgG含量均高于单纯应用CYT组更多还原

【Abstract】 Systematic experiments on the effects of He-Ne laser irradiation combined with the traditional antitumor medicine of cyclophosphamide on peripheral blood serum IgG were conducted by using the experimental model of mouse S180 ascites sarcoma. Three groups of tumor bearing mice were irradiated upon the inner corners with the dosages of 11 00, 14 67 and 22 00 J/cm 2 He-Ne laser irradiation respectively, and injected with CYT intraperitoneally to observe the changes of peripheral blood serum IgG in tumor bearing mice. The values of peripheral blood serum IgG in tumor bearing mice in the mice with CYT+ He-Ne laser irradiation treatment were higher than that with CYT treatment only. The kinetic detection of peripheral blood serum IgG indicated that CYT showed the immunosuppressive effects on the tumor bearing mice, and the immunosuppressive effects were alleviated in some degree by He-Ne laser irradiation.更多还原