【摘要】 目的　探讨早产儿机械通气的临床特点及转归。方法　回顾性分析我院NICU 2 0 0 0年 1月至2 0 0 2年 12月收治的 10 7例机械通气早产儿的临床资料 ,并与同期机械通气足月儿进行比较。结果　新生儿肺透明膜病 (HMD)是早产儿接受机械通气治疗的首要原因 ,16 8%的病例需 2次以上机械通气治疗。与足月儿相比 ,早产儿机械通气持续时间长 ,易并发颅内出血及肺出血 ;病死率较高 (2 9 0 % ) ,死亡的高危因素包括 :多胎、复苏史、出生体重 <2 0 0 0g、孕周 <34周、Apgar 5分钟评分 <5 ,及颅内出血。结论　机械通气早产儿是NICU最危重的一组病例 ,认识这组患儿的临床特征有助于更好地进行早产儿护理 ,提高其存活率和生存质量。更多还原

【Abstract】 Abstract Objective To review the clinical characteristics of ventilated preterm infants and to improve prognosis of these patients. Methods We retrospectively analysed 107 preterm infants and 86 term infants in our NICU from January 2000 to October 2002. Results Hyaline membrane disease(HMD) was the most important cause of ventilation therapy in preterm infants, 16.8% of the preterm infants needed recurrent ventilation. Compared with term infants,preterm infants had a higher risk of pulmonary hemorrhage and intracranial hemorrhage. Mortality was 29.0%.Risk factors contributing to mortality were a history of multiple birth, history of resuscitation, intracranial hemorrhage, birth weight below 2000g,gestational age below 34w and Apgar score<5 at 5 minute.Conclusion Ventilated preterm infants are among the most critical patients in the NICU.It is important to know the clinical characteristics of these infants in order to improve treatment and prognosis of preterm infants.更多还原