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尼帕病毒的研究进展
Progress in research of Nipah virus
【摘要】 尼帕病毒是单链RNA病毒 ,属于副粘病毒科 ,是 1 999年在马来西亚发现的动物病毒。基因组全长 1 82 4 6个核苷酸 ,其序列与亨得拉病毒同源性最高。尼帕病毒引起人类急性脑炎 ,病死率高。果幅是尼帕病毒的自然宿主。在马来西亚的爆发中 ,猪是大多数人类病例的传染源 ,未发现人传人传播
【Abstract】 Nipah virus is a single strand RNA virus and belongs to Paramyxoviridae family. The virus was first isolated from a 1998—1999 outbreak of acute encephalitis in Malaysia. Its complete nucleotide sequence is 18 246 nt long, with the closest relationship to Hendra virus. Nipah virus causes acute encephalitis in human, with high mortality. Flying foxes are the native reservoir of the virus. The most of patients with fatal encephalitis in Malaysia outbreaks were infected from pigs. There is no evidence of person person transmission.
【关键词】 尼帕病毒;
亨得拉病毒;
急性脑炎;
副粘病毒科;
【Key words】 Nipah virus; Hendra virus; acute encephalitis; paramyxoviridae family;
【Key words】 Nipah virus; Hendra virus; acute encephalitis; paramyxoviridae family;
- 【文献出处】 基础医学与临床 ,Basic Medical Sciences and Clinics , 编辑部邮箱 ,2004年02期
- 【分类号】R373
- 【被引频次】10
- 【下载频次】262