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以社区为基础的静脉吸毒人群丙型肝炎病毒感染危险因素研究

Community-based survey of HCV transmission risk factors among injection drug users

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【作者】 刘石柱陈康林朱国平巫俊林冯成玉范建英秦光明孙乔刘刚郑国英何益新周枫阮玉华邵一鸣

【Author】 LIU Shi-zhu 1,2, CHEN Kang-lin 3, ZHU Guo-ping 3, WU Jun-lin 3, FENG Cheng-yu 3, FAN Jian-ying 3, QIN Guang-ming 4, SUN Qiao 4, LIU Gang 4, ZHENG Guo-ying 4, HE Yi-xin 1,2, ZHOU Feng 1,2, RUAN Yu-hua 1, SHAO Yi-ming 1. 1.National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China; 2.Union School of Public Health, Peking Union Medical College, Beijing 100021, China; 3.Xichang Center for STD and Leprosy Control, Xichang 615000, China; 4.Disease Prevention and Control Center of Sichuan Province, Chengdu 610031, China

【机构】 中国疾病预防控制中心性病艾滋病预防控制中心西昌市皮肤病性病防治站四川省疾病预防控制中心中国疾病预防控制中心性病艾滋病预防控制中心 北京100050中国协和医科大学协和公共卫生学院北京100021四川西昌615000四川成都610031北京100050北京100050

【摘要】 目的 了解四川省凉山州地区静脉吸毒人群丙型肝炎病毒感染情况及其危险因素。方法 以社区为基础调查静脉吸毒人群丙型肝炎病毒感染危险因素 ,通过检测研究对象的丙型肝炎病毒抗体确定是否感染丙型肝炎病毒。结果 静脉吸毒人群丙型肝炎病毒感染率为 71.0 % (2 6 9/379)。在多因素 logistic回归模型分析中 (P<0 .0 5 ) ,共用注射器具次数的 OR值为 2 .0 5 3,其 95 %CI为 1.4 5 8~ 2 .891。在单因素χ2 分析中 (P <0 .0 5 ) ,共用注射器具次数、共用注射器具吸毒年限、近 3个月平均每天静脉吸毒频率等多个因素同丙型肝炎病毒感染有关。结论 需进一步研究阐明静脉吸毒共用注射器具方式对丙型肝炎病毒感染的影响

【Abstract】 Objective To study risk factors of HCV transmission among injection drug users (IDUs) in Liangshan, Sichuan province. Methods A community-based survey was conducted to investigate high risk behavior factors of HCV transmission and to test HCV antibody among IDUs. Results The HCV prevalence was 71.0% (269/379) among IDUs. Using a multivariate logistic regression model (P<0.05), the OR of sharing times of injection equipment in the past was 2.053,and 95% CI was 1.458~2.891. In univariate analysis, sharing times of injection equipment, sharing years of injection equipment, frequency of daily injection in the last three months, and sharing of needles, water, and vessels in the last three months were statistically significant risk factors of HCV transmission. Conclusions HCV infection risk factors such as sharing patterns of injection equipment should be investigated in the future.

【基金】 国家十五科技攻关项目 (2 0 0 1BA70 5 B0 2 )资助
  • 【文献出处】 疾病控制杂志 ,Chinese Journal of Disease Control and Prevention , 编辑部邮箱 ,2004年01期
  • 【分类号】R181.3
  • 【被引频次】9
  • 【下载频次】78
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