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沙眼衣原体感染与血清中抗精子抗体相互关系的研究

Research on the Relationship Between Chlamydia Trachomatis and Antisperm Antibody

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【作者】 粟盛梅刘传爱赵飞骏余敏君占利生唐双阳

【Author】 SU Sheng - mei, LIU Chuan - ai, ZHAO Fei - jun, et al (Institute of Pathogenic Biology, Nanhua University, Hengyang , Hunan 421001, China)

【机构】 南华大学病原生物学研究所南华大学病原生物学研究所 湖南衡阳421001湖南衡阳421001湖南衡阳421001

【摘要】 目的 探讨男性不育患者CT感染与血清中AsAb的关系。方法 应用聚合酶链反应(PCR)与ELISA法对177例男性不育患者分别进行CT和AsAb检测。结果 CT阳性者AsAb的阳性率(27.9%)明显高于CT阴性者的AsAb阳性率(8.3%,X2=12.2,P<0.01)。结论 沙眼衣原体感染可增加AsAb的产生,可能与男性不育有关。

【Abstract】 Objective To investigate the relationship between Chlamydia trachomatis(CT) and Antisperm Antibody(AsAb) in masculine infertile patients. Methods Polymerase chain reaction(PCR) and Enzyme linked immunosorbent assay(ELISA) were separately used to detect the CT and AsAb of 177 masculine infertile patients. Results The positive rate of AsAb in serum of CT infection group and CT uninfection group were 27.9% and 8.3% respectively. There was a significant difference in AsAb presence in serum between the two groups ( P < 0.01) . Conclusion The CT may increase the productivity of AsAb. It may be one of the factors leading to masculine infertility.

  • 【文献出处】 南华大学学报(医学版) ,Journal of Nanhua University(Medical Edition) , 编辑部邮箱 ,2004年04期
  • 【分类号】R698.2
  • 【被引频次】2
  • 【下载频次】33
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