【摘要】 目的　观察 5 -氟尿嘧啶 (5 -Fu)肝动脉内持续输注联合低剂量顺铂 (DDP) (肝动脉内FP方案化疗 )治疗原发性弥漫型肝癌的近期疗效和生存质量。方法　治疗组 31例接受肝动脉内持续输注 5 -Fu 5 0 0mg/d ,连用 3～ 4周 ,DDP 5mg/ (m2 .d) ,静脉输注 ,每周用 5天 ,连用 3～ 4周为一疗程。共用 2疗程。对照组接受常规介入治疗。结果　治疗组有效率 5 4 83% ,进展率 19 36 % ,卡氏评分提高率 5 4 84 %。结论　肝动脉内FP方案是姑息治疗原发性弥漫型肝癌的有效方案。更多还原

【Abstract】 Objective To evaluate the response and quality of life of continuous hepatic arterial infusion of 5-fluorouracil(5-Fu) and low-dose cisplatin(DDP)(FP therapy) for patients with hepatocellular carcinoma(HCC). Methods The patients in treatment group(31 cases)were treated by continuous hepatic arterial infusion of 5-Fu 500mg/d for 3～4 weeks,DDP 5mg/(m 2.d) infusion for 5 days each weck,repeated over 3～4 weeks as 1 cycle,and 2 cycles altogether;and those in control group underwent conventional interventional therapy -transcatheter arterial chemoembolization.Results Overall response rate 54.83% ;progress rate 19.36% in the treatment group;the karr’s score increasing rate 54.84%.Conclusion FP therapy may be useful as a pallative chemotherapy for cases of HCC(diffuse type).更多还原