【摘要】 目的　比较氯诺昔康与芬太尼、曲马多用于术后镇痛的效果及副作用。方法　烧伤择期手术患者 6 0例 ,随机分成 3组 ,各组 2 0例 :A组芬太尼 1mg ;B组曲马多10 0 0mg ;C组氯诺昔康 2 4mg ;3组均加生理盐水至总量 10 0ml,所有患者均不用首次剂量 ,在术后持续静脉输注 (2ml/h)。行 4、8、12、2 4小时及换药时疼痛评分 ;4 8小时总体评分 ;镇静评分 ;恶心、呕吐、尿潴留评分 ;并观察呼吸循环抑制情况。结果　镇痛效果 :1mg芬太尼 >2 4mg氯诺昔康 >10 0 0mg曲马多 ;4 8小时总体评分 :10 0 0mg曲马多 >1mg芬太尼 >2 4mg氯诺昔康 ;镇静评分 :1mg芬太尼 >10 0 0mg曲马多 >2 4mg氯诺昔康 ;恶心呕吐评分 :10 0 0mg曲马多 >1mg芬太尼 >2 4mg氯诺昔康。结论　氯诺昔康可替代芬太尼、曲马多 ,用于烧伤患者术后镇痛。更多还原

【Abstract】 Objective To compare the clinical efficacy and side effects of lornoxicam with tramadol and fentanyl for postoperative burnt patient analgesia.Methods Sixty burnt patients undergoing elective operation were randomly divided into 3 groups: group A receiving fentanyl 1 mg; group B subject to tramadol 1000 mg; group C administrated with lornoxicam 24 mg. The postoperative pain and side-effects were assessed.Results Lornoxicam provided more satisfactory postoperative pain relief than tramadol, the least side-effects and the most comfort in burnt patients compare with fentanyl and tramadol.Conclusion Lornoxicam provides and alternative to fentemyl and tramudol in the postoperative analgesia for burnt patient.更多还原