【摘要】 目的　探讨肺炎患儿血糖、C反应蛋白 (CRP)在全身炎症反应综合征 (SIRS)中的改变及其意义。方法　选择6 2例肺炎并SIRS患儿 ,动态测定血糖及CRP ,同时选择非SIRS的肺炎患儿和正常儿童作对照。结果　非SIRS组血糖与正常对照组比较差异无显著性 (P >0 .0 5 ) ,而CRP极显著高于正常对照组 (P <0 .0 1) ;SIRS组血糖和CRP均极显著高于非SIRS组 (P <0 .0 1) ;具有SIRS诊断标准 3项以上的患儿 4 8h血糖和第 5天CRP持续不降 (P <0 .0 1) ,发生多器官功能不全综合征 (MODS)率明显增高 (P <0 .0 1)。结论　肺炎时血糖和CRP联合检测有助于准确评估病情的危重度 ,血糖和CRP持续性升高 ,预示着MODS的可能发生。更多还原

【Abstract】 Objective To assess the changes and significance of blood glucose, C-reactive protein (CRP) in children with infantile pneumonia associated with systemic inflammatory response syndrome (SIRS). Methods Levels of blood glucose and CRP were measured in 62 children with pneumonia associated with SIRS (serving as group A), those with pneumonia of non-SIRS (as group B) and healthy children (as control group).Results There was no significant difference in blood glucose between group B and control group (P> 0.05 ), but CRP was significantly higher in group B than in control group (P< 0.01 ). The levels of blood glucose and CRP in group A were significantly higher than in group B (P< 0.01 ). The pneumonia children with three items of standard diagnostic indexes for SIRS kept high levels of 48 h blood glucose and the 5th-day CRP (P< 0.01 ), so the incidence of multiple organ dysfunction syndrome was increased significantly (P< 0.01 ).Conclusion The combined detection of blood glucose and CRP might help to accurately assess the severity of SIRS. The continuously elevated blood glucose and CRP might forecast the possibility of MODS.更多还原