【摘要】 目的　探讨子宫动脉栓塞术 (UAE)对子宫肌瘤的治疗效果 ,并对影响疗效的因素进行分析。方法　对 36例症状性子宫肌瘤患者 ,经超选择性插管双侧子宫动脉内注入PVA颗粒栓塞治疗 ,术后 3、6、12个月随访复查 ,观察患者临床症状改善和子宫肌瘤体积变化情况。结果　UAE术后患者子宫出血症状改善最为明显 ,栓塞后 3、6、12个月肌瘤体积平均缩小分别为 5 0 .5 % ,5 6 .3% ,6 1.8%。肌壁间和黏膜下肌瘤的临床症状改善和体积缩小较浆膜下肌瘤明显。结论　双侧子宫动脉栓塞治疗子宫肌瘤是一种安全有效的新方法 ;其疗效与栓塞术后肌瘤血管的重新构建 ,肌瘤类型 ,血供状态 ,子宫动脉单双侧栓塞等多种因素有关。更多还原

【Abstract】 Objective To investigate the therapeutic efficacy of uterine artery embolization in the treatment of uterine fibroids and to analyse the influential factors to the therapeutic efficacy.Methods Thirty-six patients with symptomatic uterine myomas,were treated by superselective catheterization and embolization of bilateral uterine arteries using PVA particles.Patients were followed for 3,6,12 months after uterine artery embolization.Baseline symptoms and the volume of the fibroids were used as parameters to evaluate the therapeutic efficacy.Influential factors and therapeutic efficacy were analyzed.Results The clinical symptoms,especially heavy menstrual bleeding,were improved markedly.The average of 50.5%,56.3%,61.8% volume reduction of the fibroids was achieved during the 3,6,12 months follow-up.The submucosal and intramural location of the myomas reduced more in the volume compared with that of the subserosal location.Conclusion Selective uterine artery embolization is effective for uterine myoma.Influential factors to the therapeutic efficacy may include:postprocedural vascular reconstruction in the fibroid,location of the fibroid,the modynamic status of the fibroid,and the mode of embolization(unilateral or bilateral ).更多还原