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Synthesis, Characterization and the Effect of Glucose-lowering of Guanidino Acid Oxovanadium(Ⅳ) Complexes

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【作者】 刘巨涛王晓红李建新刘景福

【Author】 LIU, Ju-Tao*,a,b WANG, Xiao-Honga LI, Jian-Xina LIU, Jing-Fua aFaculty of Chemistry, Northeast Normal University, Changchun, Jilin 130024, China bKey Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China

【机构】 Faculty of ChemistryNortheast Normal UniversityChangchunJilin 130024China Key Laboratory of Rare Earth Chemistry and PhysicsChangchun Institute of Applied ChemistryChinese Academy of SciencesJilin 130022ChinaChina

【Abstract】 Two guanidino acid oxovanadium(IV) complexes have been synthesized. Preliminary tests in vivo have shown that the two title complexes all display lowering glucose activity in vivo to STZ-rats. The effect of glucose-lowering of guanidino acetic acid oxovanadium(IV) complex in vivo is higher than that of guanidino propanoic acid oxovanadium(IV) complex.

【基金】 Project supported by the National Natural Science Foundation of China (No. 20171011).
  • 【文献出处】 Chinese Journal of Chemistry ,中国化学(英文版) , 编辑部邮箱 ,2004年07期
  • 【分类号】O631
  • 【下载频次】3
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