【摘要】 目的　探讨来自不同龋敏感者变形链球菌 (血清型 C)临床分离株产酸能力的差异。方法　配制相同浓度的各变形链球菌临床分离株菌悬液 ,分别在不同 p H下 (p H5 .0～ 7.0 )含 5 %葡萄糖的 TPY液体培养基中培养相同时间后 ,采用酸度计测定培养物终末 p H值 ,比较细菌的产酸能力 (△ p H)。结果　同一个体所带不同基因型变形链球菌菌株产酸能力有差异 ;高龋组个体定植的产酸能力强的菌株所占比例显著高于无龋组 (P<0 .0 5 )。结论高龋组变形链球菌 (血清型 C)临床株的高致龋力与其携带有产酸能力强的菌株密切相关更多还原

【Abstract】 Objective To investigate the ability of acidogenecity of S.mutans (serotype C) strains isolated from the people with different caries experience.Methods Same density solutions of all isolated S.mutans were made and cultured in different pH TPPE liquid for the same period of time. Terminal pH of the solutions was measured. The values of △pH were compared. Results Significant difference of acidogenecity was observed between the strains of different genotypes isolated from the same person. The ratio of high acidogenecity isolates harbored in caries active people was greater than that of caries free people; a significant difference was noted ( P<0.05) . Conclusion The high cariogenecity of isolated S.mutans strains of caries active people shows aclose relationship with the high acidogenecity of the isolated S.mutans (serotype C) strains.更多还原