【摘要】 三氮唑环和喹啉酮环均为抗真菌药物的基本药效基团 ,为探索二氢喹啉酮并入三唑环对抗真菌活性的影响 ,设计并合成了 7 氨基 4,5 二氢 [1 ,2 ,4]三氮唑并 [4,3 a]喹啉衍生物 ,其结构经质谱、红外光谱和核磁共振氢谱确证。更多还原

【Abstract】 Both triazole ring and quinoline ring are basically effective groups in antifungal drug.In order to know the antifungal activities after a triazole ring being added to the quinoline ring,three 4,5-dihydro[1,2,4] triazolo[4,3-a] quinoline derivatives were designed and synthesized.All of their structures were confirmed by MS、IR and 1HNMR .The pharmacological tests of them are being in process.更多还原