【摘要】 目的探讨良性骨巨细胞瘤远处转移的临床特征与治疗。方法回顾性分析我院收治的4例骨巨细胞瘤远处转移患者的临床资料。结果4例患者,男3例,女1例,年龄17～43岁。原发病灶位于股骨远端2例,股骨近端1例,桡骨远端1例。转移病灶的部位是:1例坐骨转移,2例肺转移,1例肺转移合并掌骨转移。发现远处转移的时间为最长77个月,最短3个月。随访5～84个月,1例肺转移死亡;1例行原发灶、复发灶及转移灶切除后,随访时暂无复发及新转移灶;2例手术后带瘤生存。结论骨巨细胞瘤的Jaffe分级与临床、X线表现及是否发生远处转移可能不一致。Jaffe分级为良性的骨巨细胞瘤患者也有远处转移的可能,需要长期随诊和仔细观察。更多还原

【Abstract】 Objective To study the clinical features and treatment of benign giant cell tumor of bone with distant metastasis. Methods The clinical data of 4 patients with benign giant cell tumor of bone with distant metastasis in our hospital were analyzed retrospectively. Results Of 4 patients, 3 were male and 1 was female. The age ranged from 17 to 43 years. The lesions located in distant femur 2 cases, femur neck 1 case and distant radius 1 case. There were 1 case with ischium metastasis, 2 cases with lung metastasis, and 1 case with metacarpal and lung metastasis. It took 3～77 months to make the diagnosis of distant metastasis. In the period of following-up with 5～84 months, 1 case died of lung metastasis, and 3 cases survived. Conclusion The Jaffe抯 classification of giant cell tumor of bone is not always parallel to the clinic, the X-ray showing and with or without distant metastasis. The long-term following-up and careful observation are necessary for the benign giant cell tumor of bone.更多还原