【摘要】 目的　观察α -干扰素治疗毛细支气管炎的疗效及不良反应。方法　将 10 0例呼吸道合胞病毒 (RSV)所致毛细支气管炎住院患儿随机均分为治疗组和对照组 ,治疗组以基因重组干扰素α - 2b(rIFNα - 2b)治疗 ,对照组用病毒唑治疗。结果　治疗组患儿的入院后病程及咳嗽、喘憋等主要症状和体征的缓解或消失所需的时间显著少于对照组。结论　应用rIFNα - 2b可进一步提高毛细支气管炎的治疗效果 ,且不良反应轻微 ,患儿可以耐受更多还原

【Abstract】 Objective To observe the treatment effects and the adverse reaction of bronchopneumonia with α-interferon. Methods 100 children with bronchopneumonia caused by RSV were randomly divided into treatment group and comparison group. In the treatment group, rIFNα-2b was used and in the comparison group ribavirin was used. Results After the patients being taken to hospital, the disease course, the time of release or disappearance of the main symptoms such as cough, and signs in the treatment group were obviously less than that in comparison group. Conclusion rIFNα-2b can be used to improve the treatment effects of bronchopneumonia with slight adverse reaction.更多还原