【摘要】 目的 :探讨慢性肺源性心脏病患者中 ,合并心力衰竭与未合并心力衰竭患者血清及痰中白细胞介素以及 C反应蛋白的差异。方法 :选取 12例肺源性心脏病未合并心力衰竭者及 16例肺源性心脏病合并心力衰竭者 ,进行血清、痰中白介素 - 4、白介素 - 6及血清 C反应蛋白定量检测 ,并与健康者比较。结果 :(1)两组肺源性心脏病患者中 ,合并心力衰竭血清及痰中白介素 - 4、白介素 - 6及血清 C反应蛋白的含量均较健康对照组增高 (P<0 .0 5 ) ;(2 )肺源性心脏病患者中 ,合并心力衰竭血清及痰中白介素 - 4、白介素 - 6和 C反应蛋白含量较未合并心力衰竭患者的含量增高 (P<0 .0 5 )。结论 :肺源性心脏病合并心力衰竭者炎症因子增高 ,提示心力衰竭加重了支气管的损伤程度更多还原

【Abstract】 Objective To study the difference of interleukin and C response protein in serum and sputum in chronic cor pulmonale complicated or not complicated with heart failure. Methods A quantitative determination was done in serum and sputum interleukin-4, interleukin-6 and serum C response protein in 12 cases of cor pulmonale not complicated with heart failure and 16 cases of cor pulmonale complicated with heart failure, which was compared with control group. Results ① The contents of serum and sputum interleukin-4, interleukin-6 and serum C response protein were higher in two groups of cor pulmonale than in control group (P<0.05). ② The contents of serum and sputum interleukin-4, interleukin-6 and serum C response protein were higher in the group of cor pulmonale complicated with heart failure than in the group of cor pulmonale not complicated with heart failure (P<0.05). Conclusion The inflammation factors was higher in cor pulmonale complicated with heart failure, which indicates that heart failure could worsen the injury of bronchial.更多还原