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骨松康合剂防治骨质疏松的实验研究
Experiment Study on Gusongkang Mixture for the Prevention and Treatment of Osteoporosis
【摘要】 目的 :研究骨松康合剂对骨质疏松的防治作用。方法 :选择维甲酸致大鼠骨质疏松模型及卵巢切除致大鼠骨质疏松模型 ,观察骨松康合剂的药理作用。结果 :与模型组比较 ,骨松康合剂明显增加大鼠股骨骨密度、骨近端骨小梁密度和宽度。结论 :骨松康合剂对维甲酸造成的大鼠骨质病变及对雌激素不足造成的骨质疏松有较好防治作用
【Abstract】 Objective:To study the efficacy of improving osteoporosis treated with Gusongkang Mixture.Methods:The osteoporosis models were induced by retinoic acid and ovariectomy in rats.The efficacy of Gusongkang Mixture were observed. Results:Compared with the retinoic acid group and ovariectomized group Gusongkang Mixture enhanced the bone density (BMD) of femur, the density and length of bone trabecula in rats. Conclusion:Gusongkang Mixture could improve the osteoporosises caused by retinoic acid and estrogen deficiency.
【关键词】 骨松康合剂;
维甲酸;
卵巢切除;
骨质疏松;
防治作用;
【Key words】 Gusongkang Mixture; Retinoic acid; Ovariectomy; Osteoporosis; Prevention and treatment;
【Key words】 Gusongkang Mixture; Retinoic acid; Ovariectomy; Osteoporosis; Prevention and treatment;
- 【文献出处】 湖南中医药导报 ,Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology , 编辑部邮箱 ,2004年01期
- 【分类号】R285.5
- 【被引频次】11
- 【下载频次】103