【摘要】 目的 :研究亚低温应用对高血压脑出血术后治疗效果的影响。方法 :6 5例高血压脑出血术后患者随机分为亚低温组和常规降温对照组。亚低温组 33例 ,均于术后 2h内进行亚低温治疗 ,持续 38～ 72h ,肛温维持在35 .0～ 35 .5℃。对照组 32例 ,体温维持在 37.0～ 37.5℃。 2组其他治疗相同。监测降温期间患者的体温、呼吸、血压、心率、血氧饱和度、颅内压、血糖、血电解质和血气。 2组患者均于术后 3个月按日常生活能力 (ADL)分级标准进行临床疗效评价。结果 :与对照组相比 ,亚低温治疗组患者术后高颅压、高血糖、消化道出血发生率均显著下降 (P<0 .0 5 ) ;无严重并发症 ,病死率明显降低 ,预后显著改善 (P <0 .0 5 )。结论 :高血压脑出血患者术后适时恰当应用亚低温辅助治疗 ,可降低术后病死率 ,提高患者生存质量更多还原

【Abstract】 Aim: To study the clinical effect of mild hypothermia on the postoperational patients with hypertensive intracerebral hematoma. Methods: All the patients were randomly allocated into the mild hypothermic group (33 cases)and the control group (32 cases). Mild hypothermia was performed with the mild hypothermic group within 2 h after operation and lasted for 38～72 h. The rectal temperature ranged from 35.0 to 35.5 ℃ for the mild hypothermic group, and 37.0 to 37.5 ℃ for the control. Meantime, the vital sign, intracranial pressure(ICP), blood gas values, blood electrolytes and oxygen saturation were measured. The prognosis of the patients was evaluated according to ADL. Results: In comparison with control, the incidence of high ICP, high blood glucose, and hemorrhage of digestive tract in mild hypothermia group decreased significantly ( P <0.05). The mortality decreased and the prognosis improved ( P <0.05). Conclusion: Mild hypothermia is safe and effective for preventing the postoperational patients with severe hypertensive intracerebral hematoma from brain damage, reducing the mortality and improving the prognosis.更多还原