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bFGF治疗急性缺血性脑血管病的近期疗效观察
Observing the recent curative effect of acute ischemic cranial vascular disease with bFGF
【摘要】 目的 观察基因重组碱性纤维细胞生长因子(bFGF)治疗急性缺血性脑血管病的疗效。方法 96例患者随机分成治疗组与对照组各48例,均采用支持疗法如每日给予脱水剂、酌情选用扩容、改善微循环药物。bFGF治疗组1600U/次肌肉注射,2次/d,30d为一疗程。结果 bFGF治疗组总有效率91.66%,对照组总有效率83.33%;两组治疗前神经功能缺损评分无显著差异(P>0.05)。治疗30d后两组评分较前明显下降,但以bFGF组下降显著,治疗后两组平均评分有高度显著性差异(P<0.01)。结论 表明在传统的基础上加用bFGF治疗,能取得更好疗效。
【Abstract】 Objective To observe the curative effect of acute ischemic cranial vascular disease with bFGF.Methods 96 patients were divided into 2 groups at random, 48 patients each, one was cure group and the other was reference group. All groups adopted the sustaining remedy every day, Such as giving dehydrant, expanding volume blood with extenuatory and the remedy of improving micro - circulation and so on. The bFGF cure group were injected 1600U bFGF twice every day, 30 days one course of treatment.Results The total active ratio of bFGF group was 91.6% , and the reference group’s was 83.33% , and the nervous function vitium comparison has no distinct difference (P>0.05) before cure. The comparison of two groups descent more distinct than before after 30 days cure, but the bFGF group was more great. The average comparison of two groups has great distinct difference (P<0.01) after cure.Conclusion It will receive great curative effect with bFGF on the traditional remedy.
- 【文献出处】 河南实用神经疾病杂志 ,Henan Journal of Practical Neurons Diseases , 编辑部邮箱 ,2004年04期
- 【分类号】R743.3
- 【被引频次】2
- 【下载频次】45