【摘要】 文章报道了一种有效的甘露糖3,6位选择性保护和脱保护的新方法,该方法具有条件温和,选择性好,收率高等优点。这对于用甘露糖作为糖基给体或是糖基受体,以其合成在3,6位用不同糖基修饰支化的寡糖有着非常重要的意义。由于3,6位支化的甘露糖在生物糖蛋白中有着很高的表达。合成这类寡糖对于理解它们在生物体中的作用提供了先决条件。更多还原

【Abstract】 A highly efficient method to get some 3- or 6-modified mannose/altrose derivatives as both donor and acceptor for oligosaccharide synthesis was described. All the compounds with the combination for 3-and/or 6-hydroxyl protection and/or activation (including the configuration conversion of 3-carbon atom) were obtained exclusively.更多还原